Fbxw7 proteintech

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August undefined, 2024

WebJun 20, 2013 · We were also able to show that FBXW7 mutations specifically affect the ubiquitylation and half-life of c-Myc protein, a key T-ALL oncogene. Using animals … WebFeb 19, 2024 · Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway. Biosci Rep. 2024;37: pubmed publisher . Zheng M, Xu H, Liao X, Chen C, Zhang A, Lu W, et al. Inhibition of the prolyl isomerase Pin1 enhances the ability of sorafenib to induce cell death and inhibit tumor growth in hepatocellular …

E3 Ligase FBXW7 Facilitates - Frontiers

WebMay 27, 2024 · Further studies showed that PML increased the expression of FBXW7 by inhibiting its K48-linked ubiquitination and enhanced the interaction between FBXW7 and SHP2, which negatively regulated IAV replication during infection. ... (17,168-1-AP), His-Tag (66,005-1-Ig), and Flag-Tag (66,008-2-Ig) were obtained from the Proteintech Group … WebAug 13, 2024 · Then cells were washed and further incubated with FITC or Cy3-labeled goat anti-rabbit or anti-mouse IgG (Proteintech, China) at a dilution of 1:500 at room temperature for 30 min and then stained ... boyd photography

Fam83d modulates MAP kinase and AKT signaling and is induced …

WebThere are over 360 anti-FBXW7 antibodies from over 30 different suppliers shown below. Choose from either monoclonal or polyclonal antibodies for a variety of applications, such as Western blot, ELISA, Flow Cytometry, IHC and immunofluorescence. In humans, this target is encoded by the gene, F-box and WD repeat domain containing 7 (FBXW7). WebThe plasmidsoffirefly luciferase reporter FBXW7/IGF1R-WT(wild-type miR-223-binding site in the 3 -UTR of IGF1R/FBXW7)and FBXW7/IGF1R-MUT(mutated miR-223-bindingsiteinthe3-UTR of IGF1R/FBXW7)were constructed by Genechem (Shanghai Genechem Co., Ltd; Shanghai, China). The miR-223 mimic and negative con- WebMay 16, 2024 · Figure 2 FBXW7 is differently expressed in macrophages after WT Mm infection and in the lung tissues of hosts with Mtb infection.(A) mRNA expression of … boyd principles

PLEK2 promotes cancer stemness and tumorigenesis of head and …

FBXW7 Proteintech Group 55290-1-AP product information

WebThe lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination . Guoquan ... Proteintech, USA), anti-WDR5 (1:200, Cell Signaling Technology, USA), and anti-FBXW7 (1:300, Proteintech, USA) antibodies. The results were obtained with an automatic digital slide scanning and ... WebFBXW7, also named as FBW7, FBX30, SEL10 and hAgo, is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 … guy harvey fish picturesWebJun 13, 2024 · Background: FBXW7 functions as a ubiquitin ligase tagging multiple dominant oncogenic proteins and commonly mutates in colorectal cancer. Data suggest missense mutations lead to greater loss of FBXW7 function than other gene aberrations do. However, the clinicopathologic factors and outcomes associated with FBXW7 missense … guy harvey ford truck interior

"WebApr 15, 2024 · KDM5B upregulation blocked the degradation pathway of CCNE1 by reducing the expression of FBXW7. KDM5B downregulated FBXW7 gene by … " - Fbxw7 proteintech

Fbxw7 proteintech

FBW7 couples structural integrity with functional output of …

WebFBXW7 Antibodies. Antibodies that detect FBXW7 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, … WebAug 7, 2024 · FBXW7 is a critical tumor suppressor and one of the most commonly deregulated ubiquitin-proteasome system proteins in human cancer. FBXW7 controls proteasome-mediated degradation of oncoproteins such as cyclin E, c-Myc, Mcl-1, mTOR, Jun, Notch and AURKA. Consistent with the tumor suppressor role of FBXW7, it is …

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WebRabbit anti-FBXW7 Proteintech 55290-1-AP WB 1:1000 Rabbit antioccludin Epitomics (now Abcam) ab167161 WB, IHC/IF 1:1000, (1:50/1:100) Rabbit anti-N-cadherin Proteintech 13769-1-AP ... WebJun 22, 2015 · FBXW7 (F-box and WD40 domain protein 7) is a tumor suppressor frequently inactivated in human cancers. ... The ENO1 antibody for immunohistochemistry was from Proteintech. Unless otherwise noted ...

WebSep 30, 2024 · Upregulation of FBXW7 was performed in vitro on RCC cells using the lentivirus covering coding region FBXW7 cDNA sequence, and functional tests were performed to verify FBXW7 overexpression on migration and invasion of RCC cells. Moreover, WB was employed to determine the expressions of MMP-2, MMP-9, and MMP … WebMar 30, 2024 · The endogenous peroxidase was blocked with 3% hydrogen peroxide for 15 min, and antigens were retrieved with 0.1% sodium citrate buffer for 20 min. Tissue microarray sections were added to a primary anti-FBXW7 antibody (Santa Cruz Bio, USA, 1:100) or anti-MAP4 antibody (Proteintech, China, 1:100) and incubated overnight at 4 …

WebAug 24, 2024 · Mechanistically, PLEK2 interacted with c-Myc and reduced the association of F-box and WD repeat domain containing 7 (FBXW7) with c-Myc, thereby avoiding … WebFeb 19, 2024 · Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway. Biosci Rep. 2024;37: pubmed publisher . Zheng M, Xu …

WebApr 12, 2024 · In Fig. 2a, the rabbit polyclonal anti-SREBP1 antibody (Proteintech 14088-1-AP ... Yue, P., Khuri, F. R. & Sun, S. Y. Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of ...

WebFBXW7 and Cyclin C in T-Cell Acute Lymphoblastic Leukemia. FBXW7 (also known as FBW7) is an E3 ubiquitin ligase that targets the transcriptionally active intracellular form … guy harvey jewelry collectionWebMar 29, 2024 · Background Increasing evidence suggests that FBXW7 has a high frequency of mutations in esophageal squamous cell carcinoma (ESCC). However, the function of … guy harvey fishing shirtWebApr 12, 2024 · Background Cyprinid herpesvirus 2 (CyHV-2) is a pathogenic fish virus belonging to family Alloherpesviridae. The CyHV-2 gene encoding thymidine kinase (TK) is an important virulence-associated factor. Therefore, we aimed to investigate the biological function of open reading frame 55 (ORF55) in viral replication. Methods Purified CyHV-2 … boyd printing companyWebFBXW7 human Fusion Protein 6*His from Proteintech. Produced in E.coli-derived, PET28a, with high quality purity. Cat.No. Ag28471. Products; Applications; cGMP Proteins; ... Proteintech Group, Inc 5500 Pearl … guy harvey islander baysideWebNov 15, 2024 · FBXW7 was verified as a specific E3 ligase of VDAC3. FBXW7 knockdown attenuated VDAC3 degradation by suppressing its ubiquitination, thereby increasing the … boyd printing company albany nyWeb丁香通为您提供IFNA6融合蛋白商品详情介绍：价格：￥1080，货号：AG16419-50UG，品牌：Proteintech，详见丁香通IFNA6融合蛋白商品详情页； ... FBXW7 融合蛋白￥5500. FABP7 融合蛋白￥5500. PML 融合蛋白￥5500. 详细信息; 询价记录 ... boyd project services ltdWebMar 3, 2024 · F-box and WD repeat domain-containing 7 (FBW7), also known as FBXW7 or hCDC4, ... USA), and the anti-YTHDF2 and anti-GAPDH antibodies were purchased … guy harvey hotel st augustine